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    The title says it all … investing is not about following what others say, but instead about understanding what type
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    of financial outcomes you want and how best to achieve them. This calls for independent (but informed) thinking tha
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    t is aligned to your specific needs.

    As a result of the internet there is a phenomenal amount of information availa
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    le to investors today. Companies’ financial statements are readily available, as are analysts’ reports and financia
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    l news sites that provide summary information on both the market and individual investments. One of the dangers is
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    hat investors may take such sources of information as unbiased and objective. Instead each should be viewed as just
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    what it is … a source of information presented for a specific purpose, with the information being shaped to that pu
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    pose.

    This is not to say that investors should ignore such information, but instead that they should use their own
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    judgment in sifting through it and making decisions about what investments are best for them. And in many ways the
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    articular investments made are less critical than two other factors that will impact the long term value of ones por
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    tfolio.

    How soon you get started – Many have written about the power of compounding, but it definitely bears repeat
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    ing. Regardless of how much one invests, the sooner it is begun the longer one will have for the gains to compound,
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    creating an exponential growth that will result in a much larger portfolio than if one had started later in life and
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    made larger investments.

    Don’t loose big – It takes a 100% gain to make up for a 50% loss, so it is important to a
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    oid a significant loss of capital by either investing in things that can’t or are unlikely to go down, or to take a
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    limited loss if they do. Of course everyone’s risk tolerance is different, but one of the more consistent practices
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    of the wealthy is that they tend to invest conservatively.

    Investing for your self then means being aware of what y
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    ou want, and making sure that your investment decisions are in line with your values and priorities. Although other
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    (websites, newsletters, paid advisors) can provide you with interesting and useful insights, their interests will n
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    ever be as closely aligned to your interests as your attention can and should be … focused on self.

    © 2006 Duke Oke


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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