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Okay, you've made a decision to take the plunge. Well, actually two of you made that decision. But now comes the hard part. How much will all this cost? Do you want to invite every person you've ever known to the wedding, or reduce the amount of wedding guests to just include close family and friends? This is a tough q

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

uestion to answer. Just remember, the more wedding guests, the more wedding favors, larger cake, etc. never-mind adding that per plate dinner charge. Cha ching!

If you don’t know it by now, you will learn very quickly, that weddings have become big business. Now, please understand, I’m not against that. A couple of y

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ars ago, we gave my daughter and her fianc? a very large, very beautiful wedding. (Unfortunately, we did not have such wonderful wedding favors to choose from at that point!) And it was an event that we will forever cherish and forever remember. But, we learned the hard way, that there are many decisions that are mad

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

e, even last minute, that will turn your wedding day into a financial burden that you may keep paying for years to come.

Considering all of the above, let’s start at the beginning and discuss how to make a wedding budget. We’re not just talking about your wedding “day”, but your entire wedding budget – every category

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ncluding the bridal gifts, wedding cake, gown, tux, limos, wedding favors, wedding photographer/videographer, etc. etc. etc. But, for the parents who are reading this, there is good news. Because most brides and grooms wed much older than ever (average for brides – 24, grooms – 26), most couples pay for their own wedd

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ing and reception. Actually, a full 70% pay for their entire wedding day.

Okay, back to setting up a budget. This is not very exciting and actually pretty boring. But, once you’ve become engaged, you will have romantic thoughts of bridal showers, engagement parties, wedding gowns/tux, honeymoon, and of course, the b

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

idal shower favors, and unique wedding favors! We’re sure, you’re not at all excited about sitting down with your future life mate and discussing how much this is going to cost both of you. That can take the wind out of the most exciting wedding plans! But, honestly, this budget should be set up before $1.00 is spent

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

. If you do not set up a budget, you will end up spending two to three times what you planned on.

First things first. Decide how much you can spend, whether you have the cash, need to charge certain items or whether or not you both feel to take out a loan and then pay it off with the (fingers crossed) large financial

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

gifts you’ll receive.

Secondly, you HAVE to decide on a theme. If you don’t, then you will be tempted to make impulse buys, and your budget will begin to soar. Not to mention that your wedding will also look like every other wedding that you’ve gone to, and sworn up and down that yours will NEVER be like that!

Third

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ly, if you don’t set a budget and do not decide on a theme, then the day after you get married, you/your fianc?/parents/friends, etc. will all be tempted to book the banquet hall, run out and buy a wedding dress, etc. Usually when these impulse decisions are made, there is much regret, and you soon find that you are st

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ck with something you never really wanted.

Now, down to basics. The wedding reception will account for about 50% of your wedding budget. Be careful! Choose where you will have your reception wisely! Once you place money down, you usually will lose it if you decide to cancel. Also, after you narrow down your choice

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

s, be VERY careful! Always ask what is included – cake, bartenders, waiters, security people, valet parking, coat room attendant etc. There are many hidden costs here that can send your wedding budget soaring. Okay, now that I’ve convinced you to draw up a budget, let’s get started. Come up with a total budget figure

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

Then use these percentages as a guideline.

Wedding reception = 50%
Bride’s attire = 10%
Photography/videography = 10%
Music = 10%
Flowers = 10%
Invitations/postage = 4%
Other expenses = 6%

Please understand, this is an AVERAGE. Some couples choose to spend more on the reception and

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

less on flowers. Or less on the reception and more on the honeymoon. Below, is the above percentages broken down into categories. If you make this into a list, and decide how much you will spend on each area, you will insure that your budget will stay in line.

Wedding Parties: Engagement, Bridesmaid’s Lunch, Rehears

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

l Dinner, Bridal Shower, Bridal Shower Favors

Stationary: Wedding Invitations, (Announcements, Thank You Cards, Reply Cards), Stamps, Calligraphy (if desired)

Bridal Attire: Wedding Dress, Headpiece/Veil, Shoes, Accessories, Undergarments, Hairdresser, Make-up, Nails, Pedicure, Trousseau, Alterations

Phot

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ography/Videography: Formal Portraits, Engagment, Wedding and Reception, Wedding Album, Parents’ Albums, Extra Prints, Videographer of Wedding

Flowers: Ceremony Arrangements, Unity Candle (Optional), Bride’s Bouquet, Groom’s Boutonniere, Bridesmaids/Groomsmen, Mothers’ Corsages, Reception Arrangements

Recept

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

on: Food/Caterer, Drinks, Wedding Cake, Facility Rental, Place Cards, Wedding Favors, Decorations, Tips

Music/Entertainment: Ceremony, DJ or Band

Transportation: Limousines, Parking, Valet Parking

Gifts: Maid/Matron of Honor, Bridesmaids/Flower Girls, Bride’s Parents, Groom’s Parents

Fees: Church/Ce

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

remony, Officiant

Miscellaneous: Wedding Planner (Optional), Bridal Toss (Confetti, Bubbles, etc.), Bridal Shower Favors, Monogrammed Items, Cake Accessories (Knife, Top, etc.), Hotel Accomodations, Guest Book/Pen, Champagne Flutes (Monogrammed Optional), Garter

Honeymoon: Travel (Airplane, etc.), Cruise, Accommo

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ations, Enjoyment Money, Rental Car DON’T CANCEL THE WEDDING! (thought you’d need a laugh at this point!)

You can cut all of the “non-essentials” from the above list. Or cut out a few of the guests you really didn’t want to invite anyway! Remember, PLAN before you buy. Decide on a THEME before you go into a bindin

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

g contract for a banquet hall. DO NOT buy on impulse.

One last word to the wise. This is your wedding. Enjoy it. Hopefully it will be the last time you do this. So enjoy the moments. Even when it gets crazy, and you feel you’ve gotten in over your head financially. This too shall pass. Good luck and God bless

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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