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The hardest part of the SAT Reading section for most test takers is arguably the sentence comple

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

tion. The format of sentence completion is simple. The student is given a sentence with either o

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ne or two blanks. The student then must pick the right SAT vocabulary word to fill in that blank

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

. How does the student know which of the five answer choices to pick? The answer is easy:

The d

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

finition of the correct word choice answer is in the question itself.

For example:

Judy was __

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

__________; she was so happy that she aced the SATs.

(A) Elucidated
(B) Sardonic

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

nt. Why? Because “Ebullient” means cheerful and as we can see “she was so happy” part of the que

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

tion is the definition of ebullient.

The hard part? Unfortunately the only way to prepare is ge

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

t exposure to common sat vocabulary words. Don’t worry, I prepared a SAT Vocabulary Word List wi

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

th their definitions. All of these words come from practice tests I have taken in the past and t

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

he NY Times. (which uses words frequently found on the SAT.)

Esoteric- arcane

Complacent- sati

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

fied, unworried

Admonition- warning

Incredulous- skeptical, disbelieving

Nonchalant- casual,

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

indifference

Sardonic- sarcastic, mocking

Flippant- frivolous, lacking depth, seriousness

Ico

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

noclastic one who attacks settled beliefs or institutions

Naysayer- one who denies, refuses, op

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

poses, or is skeptical or cynical about something

Pretentious- pompous ambitious

Errant- out o

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

place

Pertinent- relevant

Loquacious- wordy

Torrid- hot

Laconic- brief, terse,

Audacious-

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

bold, daring

Agape- wonder

Loquacious- wordy

Capitulation- surrender, submission

Caprice- wh

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

im, impulse

Capriciousness- indecisiveness, unpredictability

Putsch- revolt against the govern

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ment

Psychedelic- state produced by drugs

Quaint- old-fashioned, charming

Quaffable- drinkabl

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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