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    In the event of Bio threat how to mobilize Hospitals in case of biological emergencies should close except for broken bones and accidents. Instead those who believe they
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    have contracted a biological terrorist induced pathogen, virus or disease should be required to stay at home.

    Then mobile vans with specially trained technicians would
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    come to them in a grid defense program. Also involved would be a grid defense mutual assistance fill in the gap program. After the people have been inoculated with the a
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    ti virus drugs, later in the week the Car Wash Guys, this just happens to be my company, but there are 21,000 independent mobile pressure washer companies in the US curr
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    ntly. They would be scheduled to perform a decon-foam spray down of the house, cars, yard and other contaminated objects (decon-foam to be stored at fire stations and vi
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    rus serums would be stored at a military base with a couple of C-130s, and 747s available to deliver it by air to the nearest airport of the outbreak) (inoculations also
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    would be stored in Guam, Hawaii and Alaska all at military bases with Air Guard units ready to deploy with a quick manual of protocol). Each time there was any type of b
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    eakout we would have instantaneous response. People could watch TV to see what to do. Wow, the media could actually help things for a change rather than creating hysteri
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    .

    With the call centers from AT&T, Fed Ex, and other large companies assisting with call centers that are provided they are still in business, since the call centers ha
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    ve mostly been outsourced to India. Then people would not storm hospitals and infect the entire staff there who are only there to help them and others who work in and ar
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    und the hospitals and other people there for simple things.

    The Grid Defense Plan would be similar to the grid response plan for home delivery services or Pizza Deliver
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    . By combining absolute offense to our national security efforts in attacking all possible targets in hostile countries, which contain arsenals of Biological weapons and
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    this defense plan we can curb any threat to our human race from extinction or elimination of entire states populations from a terrorist or state sanctioned biological at
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    tack. It is imperative that we realize the threat of attack is real and we can head it off now. After reviewing the plans of states and cities, I was under whelmed by th
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    possible efforts they could contribute. Most have failed miserably, such as Seattle, Denver and SF. So first we gear-up for the worst and second and simultaneously get
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    he bad guys offensively.

    In this scenario small attacks no problem, large ones a little more serious. School children should be taught what to do in case of a problem a
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    d parents should be alerted in newspapers and TV. It will work, and that solves that. Be ready and able to adapt quickly. No sense in spreading anthrax, ebola, or other
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    virus laced into small pox for rapid spreading through normal human interaction. To keep it from becoming a national epidemic we simply stop the situation in it’s tracks
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    Any ideas? Email me if you believe they should remain secret and post them hear if they are simple ideas. Either way if the enemy knows we are quick to respond and defe
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    t such an act, it would not makes sense for them to make such event to serve their will, because it would be stopped quickly and strengthen our resolve and our confidenc


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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