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The lab coat is an important piece of clothing for medical professionals, research chemists and health

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

care professionals who work around hazardous chemicals. The lab coats are specially designed to offer p

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

rotection from accidental spillage of chemicals and other hazardous substances.

Until a few years back

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

lab coats were only white in color. However today there are lab coats found in various colors. The mai

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

n reason for the difference in the color of the lab coats is to differentiate the different people usin

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

g lab coats. Doctors usually wear white lab coats while nurses usually prefer using blue or green lab c

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

oats. It all depends on the organization as they are the ones who decide on the color of the lab coat t

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

be used in the organization. coat There are also different types of lab coats available today like d

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

isposable lab coats, polyester and cotton blend lab coats and polypropylene lab coats. However once the

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

lab coat is inundated by a chemical, it is important that it be removed immediately as it loses its ef

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

fectiveness. The cleaning of a lab coat cannot be done at home or in public Laundromats. It has to be h

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

anded over to professionals who specialize in hazardous waste cleaning techniques.

As the severely sta

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ined and torn lab coats have to be discarded and replaced, the disposable lab coat has risen in popular

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ity. The disposable lab coats are breathable and permits the wearer to be insulated, and ensures that t

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ey don’t overheat. Doctor lab coats usually have extra room in them so that they can be worn over stree

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

t clothes to facilitate easy access to work area.

It is important to wear the lab coat properly to ens

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ure its complete benefit. All snaps, buttons and zippers in the lab coat have to be used and sleeves ha

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ve to extend past the wrists, and should never be rolled for comfort. If it is necessary to access pock

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ets through these openings, it is necessary to do so while exercising caution as dirty hands may jeopar

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

dize your safety. These dirty hands can transfer dangerous and infectious agents through these openings

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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