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(By a former acne sufferer)

Let me put it to you straight...

I talk to loads and loads of acne sufferers every day. I assist them as much

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

as possible. Some are outstandingly successful right off the bat with what I show them. Others struggle. Those that struggle I've observed

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

hare some commonalities.

Here's a few of my observations of the pitfalls acne sufferers face and how to side-step them...

#1 Mista

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ke: They see their skin as the cause of the trouble and try to correct their skin problem...

Acne, every kind of acne, whether its

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

teen, adult, body, or cystic acne has zero to do with your skin. Now before you think I've lost my mind hear me out...

Your skin, rather th

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

e health of your skin is an external mirror of your internal system.

To overcome your acne dilemma you must eternally abandon the idea that

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

you'll be able to put a gel or cream on your skin that will cure your acne...that the problem is with your skin.

How do you fix the inner p

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

roblem? We will get to that so stay tuned.

#2 Mistake: Acne patients don't have a keen knowledge of whats really causing their acne

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

..

Some shout refined sugar causes acne. Others say too much sex, or birth control pills, or lack of birth control pills. Then oth

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ers say its bad diet or bad hygiene. While others say diet doesn't effect acne.

And plenty of other theories.

(By the way, all of them are

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

wrong. None of them are the true cause of acne.)

And because they never figure out whats really causing their acne they waste their preciou

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

time and cash on futile 'acne cures' that never addresses the the root acne cause.

The most important initial step to beating your acne di

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

lemma is to discover in detail whats causing it. (Please see my report on what's causing your acne, found at: http://www.acneyoda.com/cause

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

of_acne.html )

#3 Mistake: If they are fortunate enough to discover whats the cause of their acne is they don't have a strategy or

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

method that works to fix it...

...Or they are absent an vital part that's stopping them from fixing the problem.

So they give up

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

or awhile, only to leap on the next acne fad or quick-fix acne cream when their acne gets too painful once again. But they never correct th

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

e real cause of acne.

They end up suffering longer when they don't have to.

Please hear me...

...You deserve this gift. Make the time to

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

nderstand in detail whats really causing your acne and how to stop it. Trust me, getting this knowledge is the best use of your time in your

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

effort to cure your acne.

But be careful who you learn from...

Almost no one knows what's really causing acne. There are so many erroneou

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ideas. So who do you trust? My I suggest you listen to those who have done it, who have cured their own acne and helped others do the same

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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