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Back pain injuries can have many causes.

Playing Golf is just one of them.

Golf is one of the most popular participant games played by

millions of people. It

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

is also the cause of many back pain injuries.

By the games very nature, most people who play, regard Golf as

a pastime to be enjoyed maybe once a week, an outi

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ng with friends.

Many do not realize that their back pain could be the result of the game they love.

So, what is the cause of all this suffering?

In a word DR

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

IVING or "teeing off".

Why?

Lets go to the start of the Golfing day out.

Get up early (ish)

Have a nice big breakfast.

Drive to the Golf course.

Short walk

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

to the first tee.

Get the Driver out of the Golf bag. (Did you carry it or have you splashed out on one of the fancy electric Golf Carts?)

Are you starting to

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

realize what it is I am getting to?

Using the Driver is THE most stressful part of playing Golf, as far as your back is concerned for these reasons:

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

A full back swing (most times far too fast and jerky)

A complete reversal of direction into the forward stroke.

Full backward a

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

nd forward reversal of the hips. (The critical part of your back where the most weight sits).

A full follow through (Your hips and spine have ju

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

st been propelled through 360 degrees)

No wonder then that lots of Golfers suffer from back pain.

What can I do?

Try to address the problems before

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

they occur.

Book your game at a later time. (Your back is more at risk when you have recently risen from sleep. Later in the day can be beneficial

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

because your body naturally softens up a bit during the day)

Try not to over eat at breakfast. (Over eating can make you lethargic which w

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ill temporally cancel out the softening up process.

Try to limber up a little before you play, I am not saying get down and do forty press ups

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

. Try walking briskly to the first tee instead of sauntering.

A few stretching exercises can also help a great deal.

Have you considered this

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

;

Use an iron instead of the driver. (I can hear you laughing from here).

Using an iron is much less demanding on your back and can be beneficial to your g

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ame as far as accuracy is concerned.

How to play Golf is not the intended subject of this article so I do not intend to get into that here. I will say thoug

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

that this is something you should try, what have you got to lose? You may be surprised, I know lots of Golfers who use this strategy on the shorter hole

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

s or where accuracy is of paramount importance.

Try to practice a smooth backswing, a positive forward strike and a smooth follow through

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

with the driver. (Or iron)

Are there any remedies.

Try to remember that prevention is better than cure.

Once you back "goes" it is likely to go again at some

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

point, although the advice given here will help you get playing safely again.

As for remedies, usually a short period of rest followed by the right exercise can

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

help a lot.

Finally.

Do not be tempted to play again before your back feels right.

Remember that 80% of back pain is cured with the simple steps above.

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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