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Body lotions come in many different combinations of herbs, natural products derived from fruits, plant leaves or seeds. They work in so many ways, such as healing dry skin, improving skin’s texture, nourishin

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

g and replenishing skin’s lost natural oils as well as it restores the radiance of the skin.

I. Natural Ingredients:

1. Shea butter

Derived from the fruit kernels of the shea nut tree, it has remarkable he

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

aling and softening abilities. Studies show that shea butter has anti inflammatory effects on the skin, thus increase wound healing and improve scar appearance. From its physical make up of vitamin E, vitamin

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

A, and cinnamic acid as well as a unique fatty acid profile, this butter can moisturize and heal dry skin.

2. Sunflower oil

Is rich in vitamins E and A and very high in fatty acids that aids in restoring s

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

in moisture, natural oils and regenerates. Vitamin A encourages collagen production and is able to retain moisture.

3. Almond oil

Easily absorbed, this is an important nutrient for skin softening and condit

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ioning. With high vitamin A content, it is very suitable to dry, flaky or inflamed skin. Helps the skin to balance its loss and absorption of moisture.

4. Jojoba oil

Good for all skin types, It readily pene

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

trates the skin to nourish, moisturize and softens dry skin. Hypoallergenic and pure, it contains minerals, proteins and a waxy substance which imitates the skin’s collagen, making it supple and soft to the t

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

uch.

5. Cocoa butter

A very popular ingredient among hand and body lotions, like the shea butter, it acts as an emollient helping the skin feel soft and calm. It can also prevent and lessen stretch marks if

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

applied regularly.

6 Aloe Vera

Studies show that aloe vera can very well improve the skin’s capability to hydrate itself. It has a powerful penetrating ability which carries healthy substances through the

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

skin. With daily use, aloe vera will help maintain a healthy glowing skin. Because of its numerous biologically active ingredients, such as polysaccharides, phytosterols, glycerol, vitamins E, B & C and zinc;

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

these all contribute to the healing, scar reducing and anti inflammatory effects of aloe vera.

7. Macadamia oil

This has lubrication properties and is easily absorbed. This oil is high in monounsaturated fa

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

tty acids acting as anti oxidants to prevent deterioration and weakening of cell membrane. It is also an emollient with magnesium and thiamine, that soothes and calms. Good for mature and aging skin.

8. Glyc

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

erin

It has humectant properties, drawing moisture from the air unto the skin.

II. Choosing The Right Body Lotion For You:

- Read labels Different products have different ingredients. It is important that

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

you know what consists of the lotion that you are buying, to avoid allergies. Also choose a product labeled as a moisturizer.

- Choose a moisturizing lotion Take note of the positive changes it has done to

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

your skin. Note these changes and if you love the results, then continue using it.

- Know your skin Although many lotions are for all skin types, there are lotions which are specifically formulated for norm

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

al,dry, amd extra dry skin. It is best to buy a lotion that could address to your skin type to achieve the best results.

- Know what you need Do you need a lotion just for daily moisturizing? Or you have st

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

retch marks that needs attention too? There are hundreds of moisturizing products in the market that can improve the appearance of your stretch marks as well as nourish your skin.

- Consider your skin’s cond

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

tion If you have sensitive skin, choose a moisturizing lotion that is noncomedogenic. This means that the lotion has been proven and tested not to cause acne reactions on the skin. Likewise, unscented body l

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

otions will unlikely cause allergies.

- Consider your lifestyle If you are the type who loves spending time outdoors, you may need a lotion with ultraviolet protection, to minimize skin wrinkling and drying

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

.

- Consider the season In winter, choose a heavier lotion with shea butter or any intensive ingredient. During the summer, a lighter, well absorbed lotion with aloe vera and sunscreen protection works best

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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