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Herbs have been used in skin care from times immemorial. Ancient Ayurvedic texts in India speak of the us

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

e various herbs, such as, basil, turmeric, and saffron in skin care preparations. Herbs are now being inc

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

reasingly used in the manufacture of skin care products across the world because of their healing and rej

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

uvenating properties. Some brands do not even use artificial preservatives in their products, instead dep

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

nding on the inherent quality of certain herbs to preserve themselves.

Today, aloe vera is one of the mo

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

st popular herbs, hailed for its skin-soothing and anti-aging properties. It is used in cleansers, face w

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ashes, massage creams, sunscreens, and anti-acne products. Tea tree oil is also widely used in skin care

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

products for its antiseptic and anti-acne properties. Ginseng, sage, rosemary, witch hazel, chamomile, ca

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

endula, and arnica are also popular. They are used in the manufacture of skin care products for different

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

skin types, based on their properties.

Basil and mint are used in acne skin care because of their anti-

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

bacterial and refreshing properties. Fresh basil or mint juice can be applied everyday on pimples. Turmer

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ic is another essential ingredient in many skin care products because of its antiseptic quality. It ensur

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

s a glowing, blemish-free complexion. Fresh turmeric fingers can be ground with a little milk and applied

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

on the face and the body. Pure saffron is widely used in traditional medicinal and skin care preparation

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

s in India and the Middle East. A few almonds and saffron strands can be soaked in milk and then ground i

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

nto a paste with the milk. Mixed with rosewater, this face mask nourishes and revitalizes skin. These are

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

simple herbal skin care preparations that can be made by everybody at home. However, elaborate herbal rem

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

edies should not be attempted at home without proper knowledge of herbs and their effects.

To conclude,

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

certain herbs are very beneficial for the skin and products containing them can be used with good effect.

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

However, products of only reputed brands should be used, as the wrong mix of herbs could create problems

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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