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Full of Articles - People Still Getting Fatter - Over 1 Billion Adults Overweight Worldwide
According to Paul Zimmet "This insidious, creeping pandemic of obesity is now engulfing the entire world. It's as big a threat as
According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
global warming and bird flu." This statement was recently made at the International Congress on Obesity which is held once ever
; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.
Examples of combination products may in
Examples of combination products may in
four years.
Paul Zimmet is Foundation Director of the International Diabetes Institute, and Professor of Diabetes at Monash Uni
Paul Zimmet is Foundation Director of the International Diabetes Institute, and Professor of Diabetes at Monash Uni
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.
ersity, Melbourne, Australia, at Deakin University, Victoria, Australia, and at the Graduate School of Public Health of the Unive
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
rsity of Pittsburgh, USA. He is also co-Chair of the IDF Task Force on Epidemiology.
Acording to the World Health Organization,
Acording to the World Health Organization,
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.
Combination pro
Combination pro
ore than 1 billion adults are overweight with 300 million of them are obese.
In the United States, the latest data from the Nati
In the United States, the latest data from the Nati
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
nal Center for Health Statistics show that 30 percent of U.S. adults 20 years of age and older-over 60 million people-are obese.
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
People have been getting fatter and fatter every year for the past 25 years. And this increase is not limited to adults. The per
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
entage of young people who are overweight has more than tripled since 1980. Among children and teens aged 6-19 years, 16 percent
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
over 9 million young people) are considered overweight.
Why is this of concern? Mainly because it puts people at much higher ris
Why is this of concern? Mainly because it puts people at much higher ris
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
for diabetes, hypertension (high blood pressure), coronary heart disease, stroke, and some forms of cancer.
Of special concern
Of special concern
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.
Following aspects would a
Following aspects would a
is the growing obesity rates among children. This is not only leading to a high degree of type 2 diabetes among teenagers but als
dd to the challenges in developing combination products:
Which markets to tap where the combination products can do fairly well?
Which combination prod
Which markets to tap where the combination products can do fairly well?
Which combination prod
setting them up for shortened life spans and more health problems in their later years.
The main culprits in the alarmingly fas
The main culprits in the alarmingly fas
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
growth of child obesity are, without a doubt, fast foods. Fast foods tend to be loaded with what has become the new primary food
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
groups - salt, fat, and sugar. Any one of these ingredients in excess can easily lead to problems, but with all three you're bas
t?
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
cally begging for trouble.
What's even worse is that even so called 'health foods' are not helping with the problem. Foods adver
What's even worse is that even so called 'health foods' are not helping with the problem. Foods adver
ping new procedures for reviewing their safety, efficacy and quality.
Professional from academic institutions, pharmaceutical industries, health care indust
Professional from academic institutions, pharmaceutical industries, health care indust
ised as "low-fat" tend to compensate with "high sugar". Foods low in sugar are high in salt. And fats are in food everywhere.
So
So
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
what can we do? Some of the experts are pushing for governments to impose bans on junk foods. But that's not going to happen.
T
T
.
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
e answer is moderation. We are never going to completely get rid of fast foods. Our entire economy is geared for it. But what we
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.
Companies that provide selfless information through particip
Companies that provide selfless information through particip
an do is to watch more closely what we eat by religiously choosing the low-calorie options at your restaurants and shopping marts
tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products
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